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Three-Dimensional Thinking

The Column spoke to Noor Abdulhussain from the University of Amsterdam, about her research on 3D-printing in separation science.

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Szabolcs Feketeis currently a scientific collaborator at the University of Geneva. He is actively investigating aspects of retention modeling and fundamental attributes of LC. He is the 2023 winner of the LCGC Emerging Leader in Chromatography Award which recognizes the achievements and aspirations of a talented young separation scientist who has made strides early in his or her career toward the advancement of chromatographic techniques and applications. He recently spoke to us about his current research work and his career aspirations.

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The LCGC Blog: Optimizing Gas Chromatography Using Column Dimensions

By Tony Taylor

Optimizing gas chromatography (GC) separations typically involves making some informed choices around stationary-phase chemistry and column temperature programs

Troubleshooting Gas Chromatography: Reduced Peak Size (Loss of Sensitivity)

By Tony Taylor

There are many potential causes of reduced peak size in gas chromatography (GC), and an inexperienced GC user may not know where to begin the troubleshooting process. Here, we review potential causes for reduced peak size in GC systems.

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Aggregate and Fragment Analysis in Therapeutic Monoclonal Antibodies Using On-Line Size-Exclusion Chromatography with Native Mass Spectrometry

By Chong-Feng Xu, Jing Xu, 手机怎么挂npv, 手机怎么挂npv

Size-exclusion chromatography (SEC), with the use of ammonium acetate buffer, can be coupled on-line to electrospray ionization MS for the characterization of size variants of therapeutic monoclonal antibodies (mAbs). A quadrupole time-of-flight (QTOF) MS system was employed, and the MS method was optimized to achieve favorable sensitivity for high-mass detection, while maintaining the structural integrity of the aggregates (or high molecular weight species) and fragments (or low molecular weight species).

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By Chong-Feng Xu, Jing Xu, Zoran Sosic, Bernice Yeung

Size-exclusion chromatography (SEC), with the use of ammonium acetate buffer, can be coupled on-line to electrospray ionization MS for the characterization of size variants of therapeutic monoclonal antibodies (mAbs). A quadrupole time-of-flight (QTOF) MS system was employed, and the MS method was optimized to achieve favorable sensitivity for high-mass detection, while maintaining the structural integrity of the aggregates (or high molecular weight species) and fragments (or low molecular weight species).

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Gradient Profile Effects on Reversed-Phase Separations of Monoclonal Antibodies

By Phenomenex, Inc.

To increase the resolution, this application evaluates and optimizes the gradient program when using a bioZen WidePore C4 LC column.

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Best practices with water in the analytical lab FAQs about lab water Lab water preparation optimized

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Chinese American Chromatography Association (CACA)

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ChromAcademy

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The LCGC Blog: The Lost Art of Fundamental Electronics in Analytical Chemistry

By James Grinias

Instruction in fundamental electronics and circuit design is becoming less central to analytical chemistry education and is now a “special topic” rather than a core curriculum component. This should be a cause for concern to the entire analytical chemistry community, as the need for chemical analysts to fully understand both the chemical and electronic principles behind the data they collect is critical to the future of our field.

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By Tony Taylor

Optimizing gas chromatography (GC) separations typically involves making some informed choices around stationary-phase chemistry and column temperature programs

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Latest News

Shimadzu Announce Alzheimer's Collaboration

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ChromSoc Announce ‘Martin’ & ‘Jubilee’ Medal Winners

The Chromatographic Society have announced the winners of their 2023 ‘Martin Medal’ and ‘Jubilee Medal’ as Professor Gert Desmet, Vrije Universiteit Brussel (VUB), Belgium and Professor Deidre Cabooter, University of Leuven, Belgium, respectively.

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Adapting Well Known Chromatographic Techniques for the Analysis of Biomolecules

Sep 29, 2023

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Sep 03, 2023

Building a More Efficient Routine Lab: Approaches to Modernizing HPLC Methods with New Technologies

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Miniaturized Analytical Equipment Solves Key Challenges for Laboratories
Sometimes, great solutions for analytical laboratories come in small packages. This ebook highlights the important role that miniaturized instruments play in addressing challenges faced by laboratories.

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